이시은
- 직위(직급)
- 교수 Professor
- Contact
- 062-530-4862
- E-mail Address
- selee@jnu.ac.kr
- Website
- 홈페이지
- Major & Field of Study
- Vaccine, Immunotherapy, Drug Development, Mucosal Immunology, Host-Microbe Interaction
- Laboratory
- 교육연구관 405호 National Immunotherapy Innovation Center
세부내용
학력
- 1986-1990 전남대학교 약학사
- 1990-1992 전남대학교 약학 석사
- 1992-1996 전남대학교 약학 박사
경력
- 2000-2002: BK21 Research Professor, Chosun University
- 2002-2003: Research professor, Chonnam National University
- 2007-2009: Research fellow & Staff Research Scientist, Dept. of Medicine, University of California San Diego
연구분야
- TLR-targeted vaccine adjuvant development
- Cancer immunotherapy
- Searching for targets of new paradigm anti-microbial therapeutic modalities
주요논문
- Nguyen TD, Le DH, Dang CG, Jung HS, Choi Y, Khim K, Kim Y, Lee SE*, Rhee JH*. A combined adjuvant and ferritin nanocage based mucosal vaccine against Streptococcus pneumoniae induces protective immune responses in a murine model. Nature Communications 2025 Mar 24;16(1):2871. doi: 10.1038/s41467-025-58115-8.PMID: 40128220
- Thiruppathi J, Vijayan V, Hwang HS, Bang YJ, Loeurng V, Hong SH, Sundaram A, Park I-K, Lee SE*, Rhee JH*. Thermoresistant flagellin-adjuvanted cancer vaccine combined with photothermal therapy synergizes with anti-PD-1 treatment. Journal for Immunotherapy of Cancer 2025 Mar 21; 13(3):e010272. Doi: 10.1136/jitc-2024-010272. PMID: 40118497.
- Tan W, Thiruppathi J, Hong SH, Puth S, Pheng S, Mun B-R, Choi W-S, Lee K-H, Park H-S, Nguyen TD, Lee M-C, Jeong K, Zheng JH, Kim Y, Lee SE*, Rhee JH*. Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers. NPJ Vaccines 2024 Jun. 15; 9:108. doi.org/10.1038/s41541-024-00904-1.
- Puth S, Verma V, Hong SH, Tan W, Lee SE*, Rhee JH*. An all-in-one adjuvanted therapeutic cancer vaccine targeting dendritic cell cytosol induces long-lived tumor suppression through NLRC4 inflammasome activation. Biomaterials 2022 Jul; 286: 121542.
- Lee SE*, Li X, Kim JC, Lee J, Gonzalez-Navajas JM, Hong SH, Park I-K, Rhee JH, Raz E*. Type I Interferons Maintain Foxp3 Expression and T-Regulatory Cell Functions under Inflammatory Conditions in Mice. Gastroenterology 2012. Jul. 143(1): 145-154. Featured by Han-vit-sa, BRIC, Apr. 2012. 外 다수