학력

• 전남대학교
• 광주과학기술원

경력

• 2006.09-2008.08 Post-Doc, Columbia University Medical school, New York, USA
• 2008.09-2012.07 Research professor, Gwangju institute of Science and Technology (GIST), Gwangju, Korea

연구분야

• Novel therapeutic target for bone and cartilage diseases
• Molecular mechanisms of OA and RA pathogensis
• Novel regulator molecules and mechanisms of osteoporosis

주요논문

• Lee GS, Yang JH, Kim SJ, Tran TT, Lee SY, Park KH, Kwon SH, Chung KH, Koh JT, Huh YH, Seon JK, Kim HA, Chun JS, Ryu JH. Enhancement of Intracellular Cholesterol Efflux in Chondrocytes Leading to Alleviation of Osteoarthritis Progression. Arthritis and Rheumatology. 2025 Feb;77(2):151-162
• Tran TT, Lee GS, Huh YH, Chung KH, Lee SY, Park KH, Kwon SH, Kook MS, Chun JS, Koh JT, Ryu JH. Disruption of cholesterol homeostasis triggers periodontal inflammation and alveolar bone loss. Experimental and Molecular Medicine. 2023 Dec;55(12):2553-2563
• Lee SY, Park KH, Lee GS, Kim SJ, Song WH, Kwon SH, Koh JT, Huh YH, Ryu JH. Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss. Experimental and Molecular Medicine. 2021 Apr;53(4):591-604
• Lee SY, Park KH, Yu HG, Kook EB, Song WH, Lee GS, Koh JT, Shin HI, Choi JY, Huh YH, Ryu JH. Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice. Bone research. 2019 Dec;7(1):14
• Choi WS, Lee GS, Song WH, Koh JT, Yang JH, Kwak JS, Kim HE, Kim SK, Son YO, Nam HJ, Jin IJ, Park ZY, Kim JY, Park IY, Hong JI, Kim HA, Chun CH, Ryu JH, Chun JS. The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis. Nature. 2019 Feb;566(7743):254-258 外 다수